Creating an issue to go with my pr: #23463 to make sure it gets in with the 6.1.0 release.
Other IDE's such as VSCode and Notepad++ use Alt-Click to manage multi-cursor editing, however Spyder already used Alt-Click to jump within a document (emulating clicking on the scrollflag area). While writing multi-cursor editing it was decided to leave the shortcut for multicursor as Ctrl-Alt-Click as to not overstep existing features. For users who wish to use multicursor with the more common Alt-Click shortcut, the mouse shortcuts should be made configurable.