Revise Chapter 2 documentation: fix notation conflicts and clarify model structure#187
Revise Chapter 2 documentation: fix notation conflicts and clarify model structure#187Copilot wants to merge 2 commits intocorrelated-biomarkers-qmdfrom
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Co-authored-by: Kwan-Jenny <68584166+Kwan-Jenny@users.noreply.github.com>
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Addressed technical review feedback on antibody kinetics model documentation. Primary issues: notation collision between statistical parameters and kinetic rates, unclear model relationships, and ambiguous distributional assumptions.
Notation standardization
μ_y→γ_y,μ_b→γ_b(antibody production, pathogen replication)γ→κ(eliminates conflict with gamma notation)Model structure clarification
Before: Comparison table suggesting Teunis (2016) vs serodynamics were different models with statements about "simplifications"
After: Explicit statement that models are structurally identical; provided notation mapping table only
Distributional assumptions
Separated parameter sets to clarify where Gaussian priors apply:
y_0, b_0, γ_b, γ_y, κ, α, ρ— no Gaussian assumptionlog(y_0), log(y_1-y_0), log(t_1), log(α), log(ρ-1)— Gaussian(μ_j, Σ_{P,j})Added explicit note distinguishing where transformation enables Gaussian modeling of inherently positive/bounded kinetic parameters.
Minor
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