Open-CRAVAT is a python package that performs genomic variant interpretation including variant impact, annotation, and scoring. It has a modular architecture with a wide variety of analysis modules that are developed both by the CRAVAT team and the broader variant analysis community. Open-CRAVAT is a product of the Karchin Lab at Johns Hopkins University with funding provided by the National Cancer Institute's ITCR program.
We are pleased to announce the release of the OpenCRAVAT MCP server, a new service that makes OpenCRAVAT’s variant annotation capabilities available to AI systems and other tools through the Model Context Protocol (MCP).
Please see our blog post, or the repo to get started connecting OpenCRAVAT to the LLM of your choice.
Please see: Open-CRAVAT Docs for installation instructions and software documentation.
Please report issues using the github issue tracker above.
Check out our landing page at opencravat.org