Ensure p-values are numeric before sorting#2
Open
ryananeff wants to merge 1 commit intocran:masterfrom
ryananeff:patch-1
Open
Ensure p-values are numeric before sorting#2ryananeff wants to merge 1 commit intocran:masterfrom ryananeff:patch-1
ryananeff wants to merge 1 commit intocran:masterfrom
ryananeff:patch-1
Conversation
The p variable at some point became a list of character strings that when sorted, do not sort properly due to the number of digits in the p-value. For instance, a p-value of 0.999984 would be sorted as being larger than 0.9999864 even though it's numeric value is smaller. I believe this has the effect of increasing the q-values from the qvalue function because the list is no longer in order, so larger q-values may sometimes be treated as being smaller. This will then decrease the number of significant associations output by WGCNA.
This file contains hidden or bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.This suggestion is invalid because no changes were made to the code.Suggestions cannot be applied while the pull request is closed.Suggestions cannot be applied while viewing a subset of changes.Only one suggestion per line can be applied in a batch.Add this suggestion to a batch that can be applied as a single commit.Applying suggestions on deleted lines is not supported.You must change the existing code in this line in order to create a valid suggestion.Outdated suggestions cannot be applied.This suggestion has been applied or marked resolved.Suggestions cannot be applied from pending reviews.Suggestions cannot be applied on multi-line comments.Suggestions cannot be applied while the pull request is queued to merge.Suggestion cannot be applied right now. Please check back later.
The p variable may at some point become a list of character strings that when sorted, do not sort properly due to the number of digits in the p-value. For instance, a p-value of 0.999984 would be sorted as being larger than 0.9999864 even though it's numeric value is smaller.
I believe this has the effect of increasing the q-values from the qvalue function because the list is no longer in order, so larger q-values may sometimes be treated as being smaller. This will then decrease the number of significant associations output by WGCNA.
Therefore, either ensure that the p-values are numeric before sorting or cast it to a numeric type.